How can I publish a site created in Adobe DreamWeaver as my me.com web site?

1. Here's one solution.

2. Another fast & easy solution is to:
__A. build your website in whatever application you use
__B. test it out on your computer
__C. migrate your website to MobileMe by dragging and dropping all pertinent files into the iDisk 'Sites' folder, as illustrated below. If building more than one website on MobileMe, isolate the websites using subfolders in the iDisk 'Sites' folder.